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Acute Proctitis: therapy
Topic steroids RESOLUTION of ACUTE SYMPTOMS
(burning, pain, mucous…)
Mesalazine (5-ASA)
oral 3/day + topical 1/day
REDUCTION
of hemorragic proctitis,
NO ACTION on pain, tenesmus or frequency of defecation
Sucralphate:
Sucrose sulfate-aluminium complex that binds to the ulcer, creating a
Gibson RJ et al. Supp Cancer Care 2013
physical barriers
ACTIVE
in chronic proctitis
small
/no EFFECT in ACUTE proctitis
Sodium Butyrate
: short chain fatty acid, produced by colon bacteria, increasing blood
flow and mucosal integrity
small EFFECT
vs PLACEBO in ACUTE PROCTITIS