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Sequential vs concomitant boosting
- Existence of a dose effect vs Major
response/pCR….boosting GTV
- Seq. vs SIB: different radiobiology
meaning
- SIB with conventional or moderate
hypo
- IMRT better than 3DCRT
- From the point of view of plan
optimization:
Concomitant boosting is more efficient:
better control of the dose to OARs,
better conformity index ansd dose
homogeneity in PTVs
03/01/13
Engels 2013
46Gy/23fr, SIB 55.2Gy (no CHT)