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IGRT for rectal cancer: boost

- IGRT focused on the boost volume

(simpler assessment of margins ?)

- Rectal motion as a surrogate of

GTV/CTVboost

- Reported trend for rectal volume

reduction and for shape variation

(Njikamp 2012, Maggiulli 2012,

Raso 2015)

Maggiulli 2012

- Residual deformation error after

rigid correction: anisotropic, higher

in the first few fractions

- Relatively small «optimal» margins

reported (especially if excluding the

first fractions)….mainly 5-15 mm

- Larger motion in female pts

….to be better discussed later (IGRT & adaptive)

Raso 2015