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Pelvic OARs constraints: genitals
- Dose to vagina
(Mirabeau-Beale 2015)
- Vaginal stenosis did not correlate with
DVH/dose statistics of vagina/external genitals
in a group of 52 pts treated with IMRT RT+CHT
(50-54Gy) for anal canal ca. Lower age as a
major risk factor
- Most part of vagina often included in PTV
(median dose ≈ 55Gy)
- Need of more studies
- Potentials of image-guided IMRT to spare
vagina to be still assessed (room for vagina-
sparing trials ? Volumes definition issues)
- Practical suggestion: spare vagina and external
genitals outside PTV «as much as possible»
(no relevant interplays with other structures)
Mirabeau-Beale 2015