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Pelvic OARs constraints: genitals
- Dose to penile bulb (PB)/structures
involved in erection
- Most experience from prostate ca RT
- Controversial results, some evidence for
constraining PB<40-50Gy
- Lack of prospective trials including dose-volume
data (no data to my knowledge in the rectal ca.
context)
- Very relevant «confounding» factors: baseline
situation, ageing, vascular problems,
psychological aspects
- Prospective data suggests that avoiding overlap
between PTV and PB may largely reduce erectile
dysfunctions
Cozzarini 2016
prostate ca pts, IIEF1-5 based impotence