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ART optimization based on early response ?

- Analyses of MRI-based T

regression correlated with pCR

- May Mid-RT MRI (average

volume reduction: -56%) predict

the pathological response ?

- A poisson-based radiobiological

model, incorporating the

individual early response, well

predicts pCR and residual cells

(Raso, ESTRO 2016)

- Potentials for selection of pts for

ART and adaptation of boost

dose (work in progress…)

MRIpre

mid

post

Surg

28cc

7cc

1cc

pCR