701 / 1068
CAO/ARO/AIO-Experimental Track
Phase I/II: Inclusion of molecular-targeted therapy
RT
Cap
T1
Ox
T8
T22 T29
T
M
E
CET
Rödel C. et al., Int J Radiat Oncol Biol Phys 2008
Weiss C. et al., Int J Radiat Oncol Biol Phys 2010
Fokas E., et al., Int J Radiat Oncol Biol Phys 2013
CET-CAPOX-RT
(n=45)
CAPOX-RT
(n=95)
Complete TRG (%)
9
18
Intermediate TRG /%)
55
68
Poor TRG (%)
36
15
Biomarker Studies
Grimminger PG. et al., Clin Cancer Res 2011
Hu-Lieskovan S. et al., Clin Cancer Res 2011