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MRI-staged T2-3 N0 or T any N+

R

E

S

T

FOLFOX/

CAPOX

(16-18 weeks)

RT 50.4 Gy +

5-FU/Cape

Signi-

ficant

response

N

O

M

MSKCC-Trial

(randomized phase II)

A

G

I

N

G

FOLFOX/

CAPOX

(16-18 weeks)

No

signi-

ficant

response

T

M

E

R

RT 50.4 Gy +

5-FU/Cape