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Chinese Study

Inclusion criteria: cT3-4 or N+

R

RT 50 Gy

(@2.0 Gy)

+

Capecitabine 1600 mg/m²

days 1-14 + 22-25

T

M

E

FOLFOX

6-8 cycles

Primary endpoint: 3y-OS (84 to 96%); 206 pts

RT 50 Gy

(@2.0 Gy)

+

Capecitabine 1600 mg/m²

days 1-14 + 22-25

Oxaliplatin 60 mg/m² d 1, 8 + 22, 29

T

M

E

FOLFOX

6-8 cycles