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Rectal Cancer Stage II/III

Disease-free Survival

Colon Cancer Stage II/III

n

Absolute

Difference

HR P-value

MOSAIC

2246

5% (3y)

0.77 .002

NSABP C-07

2407

4% (3y)

0.80 .003

Neoadjuvant oxaliplatin

ACCORD 12

584

4.3% (5y)

0.86 0.25

NSAPB R-04

1284

5% (5y)

0.91 0.34

CAO/ARO/AIO-04

1236

4.7% (3y)

0.79 0.03

Chinese

206

10.6% (3y)

n.g.

0.08

STAR-01 and

full paper of

PETACC-6 pending