801 / 1068
15
Intergroup RTOG 98-11: conclusions
• CCR with FU/MMC /5FU has a significant
impact on DFS and OS versus induction plus
concurrent FU/CDDP
• CCR with FU/MMC /5FU has borderline
significance for CFS, CF and LRF
MMC/5FU remains the standard of care for
patients with anal canal carcinoma
ACT-II
James, Lancet Oncol 2012