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Version 2.2015, 03/11/15 © National Comprehensive Cancer Network, Inc. 2015, All rights reserved.

The NCCN Guidelines® and this illustration may not be reproduced in any form without the express written permission of NCCN®.

MS-101

NCCN Guidelines Index

Breast Cancer Table of Contents

Discussion

NCCN Guidelines Version 2.2015

Breast Cancer

intergroup trial (E1193). J Clin Oncol 2003;21:588-592. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/12586793

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464. Gennari A, Stockler M, Puntoni M, et al. Duration of chemotherapy

for metastatic breast cancer: a systematic review and meta-analysis of

randomized clinical trials. J Clin Oncol 2011;29:2144-2149. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/21464403

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465. Falkson G, Gelman RS, Pandya KJ, et al. Eastern Cooperative

Oncology Group randomized trials of observation versus maintenance

therapy for patients with metastatic breast cancer in complete remission

following induction treatment. J Clin Oncol 1998;16:1669-1676.

Available at:

http://www.ncbi.nlm.nih.gov/pubmed/9586877 .

466. Muss HB, Case LD, Richards F, et al. Interrupted versus

continuous chemotherapy in patients with metastatic breast cancer. The

Piedmont Oncology Association. N Engl J Med 1991;325:1342-1348.

Available at:

http://www.ncbi.nlm.nih.gov/pubmed/1922236 .

467. Cortes J, O'Shaughnessy J, Loesch D, et al. Eribulin monotherapy

versus treatment of physician's choice in patients with metastatic breast

cancer (EMBRACE): a phase 3 open-label randomised study. Lancet

2011;377:914-923. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/21376385

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468. Kaufman P, Awada A, Twelves C, et al. A phase III, open-label,

randomized, multicenter study of eribulin mesylate versus capecitabine

in patients with locally advanced or metastatic breast cancer previously

treated with anthracyclines and taxanes [abstract]. Cancer Res

2012;72( Suppl 24):Abstract S6-6. Available at:

http://cancerres.aacrjournals.org/cgi/content/meeting_abstract/72/24_M

eetingAbstracts/S6-6

.

469. Roche H, Yelle L, Cognetti F, et al. Phase II clinical trial of

ixabepilone (BMS-247550), an epothilone B analog, as first-line therapy

in patients with metastatic breast cancer previously treated with

anthracycline chemotherapy. J Clin Oncol 2007;25:3415-3420.

Available at:

http://www.ncbi.nlm.nih.gov/pubmed/17606972

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470. Thomas E, Tabernero J, Fornier M, et al. Phase II clinical trial of

ixabepilone (BMS-247550), an epothilone B analog, in patients with

taxane-resistant metastatic breast cancer. J Clin Oncol 2007;25:3399-

3406. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/17606975 .

471. Perez EA, Lerzo G, Pivot X, et al. Efficacy and safety of

ixabepilone (BMS-247550) in a phase II study of patients with advanced

breast cancer resistant to an anthracycline, a taxane, and capecitabine.

J Clin Oncol 2007;25:3407-3414. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/17606974

.

472. Miller K, Wang M, Gralow J, et al. Paclitaxel plus bevacizumab

versus paclitaxel alone for metastatic breast cancer. N Engl J Med

2007;357:2666-2676. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/18160686

.

473. Miles DW, Chan A, Dirix LY, et al. Phase III study of bevacizumab

plus docetaxel compared with placebo plus docetaxel for the first-line

treatment of human epidermal growth factor receptor 2-negative

metastatic breast cancer. J Clin Oncol 2010;28:3239-3247. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/20498403

.

474. Robert NJ, Dieras V, Glaspy J, et al. RIBBON-1: Randomized,

double-blind, placebo-controlled, phase III trial of chemotherapy with or

without bevacizumab (B) for first-line treatment of HER2-negative locally

recurrent or metastatic breast cancer (MBC) [abstract]. J Clin Oncol

2009;27(Suppl 15):Abstract 1005. Available at:

http://meeting.ascopubs.org/cgi/content/abstract/27/15S/1005

.

475. Robert NJ, Dieras V, Glaspy J, et al. RIBBON-1: randomized,

double-blind, placebo-controlled, phase III trial of chemotherapy with or

without bevacizumab for first-line treatment of human epidermal growth

factor receptor 2-negative, locally recurrent or metastatic breast cancer.

J Clin Oncol 2011;29:1252-1260. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/21383283

.

476. O'Shaughnessy J, Miles D, Gray RJ, et al. A meta-analysis of

overall survival data from three randomized trials of bevacizumab (BV)