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Version 2.2015, 03/11/15 © National Comprehensive Cancer Network, Inc. 2015, All rights reserved.

The NCCN Guidelines® and this illustration may not be reproduced in any form without the express written permission of NCCN®.

MS-103

NCCN Guidelines Index

Breast Cancer Table of Contents

Discussion

NCCN Guidelines Version 2.2015

Breast Cancer

488. Burstein HJ, Keshaviah A, Baron AD, et al. Trastuzumab plus

vinorelbine or taxane chemotherapy for HER2-overexpressing

metastatic breast cancer: the trastuzumab and vinorelbine or taxane

study. Cancer 2007;110:965-972. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/17614302

.

489. Robert N, Leyland-Jones B, Asmar L, et al. Randomized phase III

study of trastuzumab, paclitaxel, and carboplatin compared with

trastuzumab and paclitaxel in women with HER-2-overexpressing

metastatic breast cancer. J Clin Oncol 2006;24:2786-2792. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/16782917

.

490. Schaller G, Bangemann N, Weber J, et al. Efficacy and safety of

trastuzumab plus capecitabine in a German multicentre phase II study

of pre-treated metastatic breast cancer [abstract]. J Clin Oncol

2005;23(Suppl 16):Abstract 717. Available at:

http://meeting.ascopubs.org/cgi/content/abstract/23/16_suppl/717

.

491. Yamamoto D, Iwase S, Kitamura K, et al. A phase II study of

trastuzumab and capecitabine for patients with HER2-overexpressing

metastatic breast cancer: Japan Breast Cancer Research Network

(JBCRN) 00 Trial. Cancer Chemother Pharmacol 2008;61:509-514.

Available at:

http://www.ncbi.nlm.nih.gov/pubmed/17516068

.

492. Seidman A, Hudis C, Pierri MK, et al. Cardiac dysfunction in the

trastuzumab clinical trials experience. J Clin Oncol 2002;20:1215-1221.

Available at:

http://www.ncbi.nlm.nih.gov/pubmed/11870163

.

493. Bartsch R, Wenzel C, Altorjai G, et al. Capecitabine and

trastuzumab in heavily pretreated metastatic breast cancer. J Clin Oncol

2007;25:3853-3858. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/17679724

.

494. von Minckwitz G, du Bois A, Schmidt M, et al. Trastuzumab

beyond progression in human epidermal growth factor receptor 2-

positive advanced breast cancer: a german breast group 26/breast

international group 03-05 study. J Clin Oncol 2009;27:1999-2006.

Available at:

http://www.ncbi.nlm.nih.gov/pubmed/19289619

.

495. Von Minckwitz G, Zielinski C, Maarteense E, et al. Capecitabine

vs. capecitabine + trastuzumab in patients with HER2-positive

metastatic breast cancer progressing during trastuzumab treatment:

The TBP phase III study (GBG 26/BIG 3-05) [abstract]. J Clin Oncol

2008;26(Suppl 15):Abstract 1025. Available at:

http://meeting.ascopubs.org/cgi/content/abstract/26/15_suppl/1025

.

496. Verma S, Miles D, Gianni L, et al. Trastuzumab emtansine for

HER2-positive advanced breast cancer. N Engl J Med 2012;367:1783-

1791. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/23020162

.

497. Baselga J, Gelmon KA, Verma S, et al. Phase II trial of

pertuzumab and trastuzumab in patients with human epidermal growth

factor receptor 2-positive metastatic breast cancer that progressed

during prior trastuzumab therapy. J Clin Oncol 2010;28:1138-1144.

Available at:

http://www.ncbi.nlm.nih.gov/pubmed/20124182

.

498. Cortes J, Fumoleau P, Bianchi GV, et al. Pertuzumab

monotherapy after trastuzumab-based treatment and subsequent

reintroduction of trastuzumab: activity and tolerability in patients with

advanced human epidermal growth factor receptor 2-positive breast

cancer. J Clin Oncol 2012;30:1594-1600. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/22393084

.

499. Geyer C, Forster J, Lindquist D, et al. Lapatinib plus capecitabine

for HER2-positive advanced breast cancer. N Engl J Med

2006;355:2733-2743. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/17192538

.

500. Cameron D, Casey M, Oliva C, et al. Lapatinib plus capecitabine in

women with HER-2-positive advanced breast cancer: final survival

analysis of a phase III randomized trial. Oncologist 2010;15:924-934.

Available at:

http://www.ncbi.nlm.nih.gov/pubmed/20736298

.

501. Blackwell KL, Burstein HJ, Storniolo AM, et al. Randomized study

of lapatinib alone or in combination with trastuzumab in women with

ErbB2-positive, trastuzumab-refractory metastatic breast cancer. J Clin