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Local control – advanced treatment adaptation

including interstitial brachytherapy

(RetroEMBRACE

Width in MRI at

diagnosis

Local control at 5 year (%)

Limited

adaptation

Advanced

adaptation

CTV

HR

<30cm

3

95%

94%

CTV

HR

≥ 30cm

3

77%

86%

The use of advanced adaption including interstitial BT

improves local control in tumors with

CTV

HR

≥ 30cm

3

and does not increase late morbidity

Fokdal et al. 2016. Fortin et

al.to

be submitted