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Quantification of tumor regression, Set-up errors and Internal Organ

Motion in locally advanced Cervical cancer treated with radical radiation -

results from a prospective study

TMH data (unpublished)

Cervical cancer with intact Uterus

N = 70 patients with FIGO IIB-IIIB

(3 out of trial)

May 2011- March 2017

Daily CBCT- IGRT (3DCRT/IMR plan)

Online/Offline: CTV nodal/primary mid-cervix and uterine matching

Baseline MRI and Mid-RT MRI = To evaluate tumor Regression

N = 67

N = 27

(SUBGROUP)

Mean cervical tumor volume reduced from 55.2 cc at

diagnosis to 28.9 cc at mid treatment.

Tumor regression