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MEMORANDUM
Date:
To:
From:
Subject:
February 10, 2016
Official Methods Board
Scott Coates, AOAC Chief Scientific Officer
Item II. b. Updating Appendix F
BACKGROUND
Appendix F: Guidelines for Standard Methods Performance Requirements (SMPR) was drafted in the
2009 – 2010 timeframe. Since 2010 AOAC has developed and adopted more than 60 SMPRs. The SMPR
process has evolved since 2010 and some of the descriptions of processes have become obsolete, and
frankly some sections are not needed any more. A revised, streamlined version of Appendix F is
attached as attachment 1. An original Appendix F is attached as attachment 2 for reference.
Discussion
1) Most of the proposed changes are sections that have been removed from the narrative descriptions
in the first 4 pages. An outdated Figure 1 has been replaced with a schematic that better represents
the process as it occurs today.
2) The term “Intermediate repeatability/reproducibility” is added to table A1, defined in table A2, and
evaluation recommendations provided in table 3.
3) The term ”LOQ” replaced by “Limit of determination (LOD)” in table A1
4) Question for OMB: the Guideline identifies “bias” as one of recommended parameters, but “bias”
has never been used in an SMPR. The terms “accuracy” or “recovery” are routinely used in SMPRs.
Should we recommend “bias” to the working groups now working on SMPRs? Or should we replace
“bias” in Appendix F with “accuracy” or “recovery”?
AOAC OMB Meeting
February 10-11, 2016
51