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Parameter
Method Performance
Please
report in units as stated in SMPR!
Weighting
factor for
parameter
Suitability Ranking (1-
3-5)
(select from drop-down
list, 5 = best)
SPIFAN matrices
Applicable to all forms of infant, adult, and/or pediatric
formula (powders, ready-to-feed liquids, and liquid
concentrates).
Any combination of milk, soy, rice, whey, hydrolyzed
protein, starch, and amino acids, with and without intact
protein.
SLV Test Material Kit for FOS provided by
Covance
1
All analytes defined in the
applicability statement are
measured.
Fructans
g/100g reconstituted final product
1
0,03 - 5,0%
Analyte 1
not relevant
Analyte 2
Analyte 3
Analyte 4
Analyte 5
Analyte 1
≤
0,03
≤
0,03
Analyte 2
Analyte 3
Analyte 4
Analyte 5
Spike recovery (%)
90-110% of mean spiked recovery
100.3
2
Bias vs SRM
no SRM available
not applicable
3
≤
6%
6
7
≤
12%
b
Units
Limit of quantification (LOQ)
Method Reference #
AOAC 997.08
Method title:
Principle of the method:
Fructans in food products
enzymatic chromatographic method
SMPR Requirement
Analytical Range.
1
Notes:
Overall Score
Intermediate Reproducibility
(RSDiR)
Recommendation of ERP
2 years after First Action Status
Laboratory safety
Other Considerations
Evaluation of Method Performance vs. SMPR requirements.
Feedback from Users of the Method since being awarded
First Action
Official Methods
Status
Repeatability (RSDr)
Reproducibility (RSDR)
Accuracy/Recovery
ADDITIONAL EVALUATION PARAMETERS
AOAC SMPR: 2014.002
Limit of detection (LOD)
1
a
Concentrations apply to (1) "ready to feed liquids" "as-is"; (2) reconstituted powders (25 g into 200 g water); and (3) liquid concentrates diluted 1:1 by weight.
Did Method Author Consider ERP’s Method Specific
Recommendations
(See web link to specific method
comments):
Decision by ERP
Proprietary equipment
move to Final Action/repeal/remove/expand 2 year term
0
No unique proprietary equipment/accessories are required.
Method does not require any special safety precautions e.g. personal protection from highly toxic solvents.
3
1
2
Bias against established method
Analytical equipment
1
Adequate proof of performance via system suitability
Is there a bias Yes/No ?
Analytical equipment is commonly available in most labs.
SPIFAN ERP Checklist v 1.6
27.06.2013
Fos-01 (February 2016) - MEF
FOR ERP USE ONLY
DO NOT DISTRIBUTE