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Classic palliative schedules
• No difference
in results between
conventional and hypofractionated
schedules
(Porccedu S R&O 2007, Cory J
R&O 2006)
• Schedules:
• 5 x 4 Gy
• 10 x 3 Gy
• 16 x 3 Gy
• Split course: 2 x 25 Gy in 10 fraction
separated by two weeks
• Overall response rate: 73%
• Median survival time was average 17
months
• Acute
grade 3 skin and mucosal
toxicities were observed in 45% and
65% of patients, respectively.
(Al.
Mamgani A, Acta Oncol 2009)
JK 45/49