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Beyond classic palliative schedules
• RTOG 85-02
: 3,7Gy twice daily over 2 consecutive days
at 2 to 3 week intervals up to a total dose of 44 Gy
• 37% completed three cycles of the regimen.
• 65% palliative response.
• Median OS was 5.67 months
(Lok B. Oral Oncol 2015)
• „0-7-21”
: 3 x 8 Gy day 0,7,21
• 31% complete tumor response
• 40% complete symptoms response
• OS 50% patients survive at least 6 mts
• Tumor volume predictive for OS and PFS, TNM stage for response level.
(Nguyen A BJR 2014)
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