155 / 1224
/
Adverse effect of WBI on neurocognitive fraction already
after 3 months
Brain metastases
NCCTG N0574 (Alliance): A phase III randomized trial of whole brain radiation
therapy (WBRT) in addition to radiosurgery (SRS) in patients with 1 to 3 brain
metastases
Brown ASCO 2015
Cognitive function
deterioration
@ 3 months
SRS
SRS + WBI
immediate recall
8%
31%
delayed recall
20%
51%
verbal fluency
2%
19%
ESTRO SBRT COURSE 2016 - Matthias Guckenberger
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