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• Conventional radiotherapy = Short term palliation

Patients with better OS will develop pain recurrence

Palliative RT

Pain response

Duration

Prince

1986

1 x 8Gy

10 x 3Gy

73%

64%

59% @ 3 mo

50% @ 3 mo

Gaze

1997

1 x 10Gy

5 x 4.5Gy

84%

89%

Median 3.5 mo

Median 3.5 mo

Steenland

1999

1 x 8Gy

6 x 4Gy

72%

69%

Median 5 mo

Median 6 mo

Roos

2005

1 x 8Gy

5 x 4Gy

61%

53%

Median 3.5mo

Median 5.5 mo

Painful bone / vertebral metastases

ESTRO SBRT COURSE 2016 - Matthias Guckenberger

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