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How large should the margin be?
What is the incentive?
99% of the target volume receives 95% of the prescribed dose or more
(coverage probability) -
Stroom et al.
90% of patients in the population receives a minimum cumulative CTV
dose of at least 95% of the prescribed dose -
van Herk et al.
Not all patients will be treated to 100%
of the prescription dose in all fractions
M = 2.5
Σ
+ 0.7
σ