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Systematic Errors Only (M

sys

= 2.5

Σ

)

The systematic set-up errors are described by a 3D Gaussian distribution

How to choose M

sys

to ensure a high probability that the prescribed dose is

delivered to the CTV?

Choice:

for 90% of all possible systematic set-up errors (treatments), the full

CTV is within the PTV (=95% isodose)

95%