Folie 1

Discussion: Clinical Relevance

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Should we measure intra-fraction motion?

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Yes, at planning in order to individualize the safety margin

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And if necessary to reduce the motion amplitude with compression

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Should we correct for intra-fraction motion?

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The penumbra is more sharp in liver than in lung

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Amplitude has an effect on the margin

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Still systematic uncertainties dominate the required margin

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Should we correct for inter-fraction motion?

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YES!

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Should we adapt the treatment plan?

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First solve issues mentioned above