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Complete pain response is achieved in 25 – 40% of
the patients
# patients
Fractionation
Complete pain response
Prince 1986
288
1 x 8Gy
10 x 3Gy
45%
28%
Gaze 1997
280
1 x 10Gy
5 x 4.5Gy
39%
48%
Steenland 1999
1171
1 x 8Gy
6 x 4Gy
37%
33%
Roos 2005
272
1 x 8Gy
5 x 4Gy
26%
27%
Complete pain control with conventional
radiotherapy for bone metastases
Spine SBRT - Matthias Guckenberger
6