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21.05.14 |

StefanDelorme

Division ofRadiology

Slice selection

Concept

z gradient and HF puls simultaneous

Only spins in one slice will be excited

B

(z)

HF

21.05.14 |

StefanDelorme

Division ofRadiology

Fourier

Trans-

formation

k-space

Image

k-space

21.05.14 |

StefanDelorme

Division ofRadiology

T2-weighted images

Bright:

Long T2:

Fat (moderately)

Blood

Fluid

Many pathologies

Dark:

Short T2:

After Gd-DTPA (slightly)

Bone, calcium

Blood (Hämosiderine)

Flow: Signal void

Lack of protons: Air

CSF

Brain

Bone

Vessels

Edema

Tumor

21.05.14 |

StefanDelorme

Division ofRadiology

Contrast medium: Gd-DTPA

GD3+ is paramagnetic

Reduces relaxation times in tissue

Affects mainly T1

Toxic if liberated, inert as a DTPA chelate

Other chelates: DOTA, DTPA-BMA, etc.

Excreted in urine

Administration i.v., oral possible

21.05.14 |

StefanDelorme

Division ofRadiology

T1-weighting

Bright

:

Short T1:

Fat

Blood (age !)

After Gd-DTPA:

disturbed BBB

Fluid with high protein

content

Dark

:

Long T1:

Free water

Bone, calcium

Flow: signal void

Lack of protons: air

Fat

Gd-DTPA

Brain

CSF

Bone

Tumor

21.05.14 |

StefanDelorme

Division ofRadiology

Outline

Computed tomography

How it works

Strengths

Weaknesses

Magnetic resonance imaging

How it works

Strengths

Weaknesses

Ultrasound

How it works

Strengths

Weaknesses