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CTV L4-L3: 1-3 N+: INDICATIONS

Randomized trials are PENDING:

RTOG 9915 (SWOG)

EORTC (SUPREMO – Selective Use of Postoperative Radiotherapy After Mastectomy): In

this trial, apart from randomize 1-3 N(+) patients, pT2 pN0 with grade 3 and/or

vasculo-lymphatic invasion are also randomized.

NCI CTG

French study

11.5%

7.9%

EBCTG META-ANALYSIS: POSITIVE RESULTS OF SURVIVAL 1-3 N+