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CTV L2-L1: INDICATIONS
– No or inadequate lymphadenectomy (L)
RT L4-L3-L2-L1
– Bulky nodal disease
– SN
(+)
(Macrometastases)
without
lymphadenectomy.
AMAROS Trial (EORTC)
(Adjuvant Management of the Axilla
Radiotherapy of Surgery) is comparing L vs axillary RT with SN (+).
RT L4-L3-L2-L1
(Micrometastases: no RT)
AMAROS
Donker 2014 Lancet Oncol
Including 4800 patients demonstrated that axillary RT is as
effective as axillary surgery with less morbidity at 5 year follow-up.