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Consequences for GTV delineation:

I

Stage I / SABR:

Delineation on CT of all (8) phases of the respiratory cycle

ITV generated on 3D-FDG-PET is NO surrogate!!

Automatically segmented 4D-FDG-PET may provide additional information

I

Advanced stage:

Delineation of target volume on CT of 3 respiratory phases – i.e.,

0%/50%/100% exspiration

FDG-PET provides additional information, e.g. Atelectasis.

Respiration correlated FDG-PET/CT

Troost

et al.

, in preparation