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“Delineating the CTV is more an art than a science because current
imaging techniques are not capable of detecting subclinical tumor
involvement directly”.
Perez & Brady, 2008
Perez & Brady.
In: Principles and practice of radiation oncology.
Lippincott Williams & Wilkins.
2008:228.
ICRU report 83
. 2010;10:44-45.
How do we define the CTV?
The clinical target volume (CTV)
Defining the CTV:
1. Probability of microscopic tumor extension: 5-10%.
2. Methods:
•
Volumetric (isotropic) expansion using margins.
•
Anatomic/compartmental: including anatomic compartments bounded by
anatomic barriers.