855 / 1311
(1)
Mcdonald JS et Al – New Engl J Med – 2001
(2)
Cunningham D et Al – New Engl J Med – 2006
Stage I
Surgery
if T2 or N1 postop. Chemoradiation
Chemorad before surg in clinical trial
Stage II
Surgery + postop. Chemoradiation
(1)
+ periop. Chemotherapy
(2)
Chemorad before surg in clinical trial
Stage III
Surgery (if no extensive nodal involvement)
+ postop. Chemoradiation
(1)
+ periop. Chemotherapy
(2)
Chemorad before surg in clinical trial
Stage IV M-
Surgery (if no extensive nodal involvement)
+ postop. Chemoradiation
(1)
+ periop. Chemotherapy
(2)
Stage IV M+
Chemotherapy
Treatment Guidelines