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➢
Calculated BED values are normalized to
conventional EBRT with 2 Gy / fraction (reference schedule) :
BED = D [ 1 + g
d / (
/
) ] = D
2Gy
[ 1 +
2
/ (
/
) ]
Mathematical Description /Normalization -
EQD2
➢
BED is the virtual dose value that produces the same biological effect
as the physical dose with an infinite low dose rate
Intro
Mission
Concept
Solution
Practice
➢
To calculate the total isoeffective dose D
2Gy
of a combined treatment, all
isoeffective doses D
2Gy
are added up :
D
2Gy,
TOTAL
= D
2Gy,
EXTERNAL
+ D
2Gy,
BRACHY
g