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Values of biological parameters

Tumour and early reacting normal tissue:

/

~ 10 Gy

7 – 20 Gy for most tumours

9 – 10 Gy for cervix carcinoma

T

1/2

~ 1.5 hours

0.5 – 1.5 hours

Late reacting normal tissue:

/

~ 3 Gy

0.5 – 6 Gy

3 – 4 Gy for bladder, rectum,

sigmoid

T

1/2

~ 1.5 hours

1 – 2 hours

Clinical and experimental experience

0

2

4

6

8

10

12

14

16

18

20

22

24

26

28

30

0

1

2

3

4

5

6

7

8

9 10

nominal Dose (Gy/fraction)

EQD2 (Gy/fraction)

Intro

Mission

Concept

Solution

Practice