Values of biological parameters
•
Tumour and early reacting normal tissue:
/
~ 10 Gy
7 – 20 Gy for most tumours
9 – 10 Gy for cervix carcinoma
T
1/2
~ 1.5 hours
0.5 – 1.5 hours
•
Late reacting normal tissue:
/
~ 3 Gy
0.5 – 6 Gy
3 – 4 Gy for bladder, rectum,
sigmoid
T
1/2
~ 1.5 hours
1 – 2 hours
Clinical and experimental experience
0
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
0
1
2
3
4
5
6
7
8
9 10
nominal Dose (Gy/fraction)
EQD2 (Gy/fraction)
Intro
Mission
Concept
Solution
Practice