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Rectal dose volume effects (2cm

3

)

≥G2 rectal morbidity (bleeding)

(Vienna cohort, n=145)

≥G2 rectal morbidity

(EMBRACE cohort, n=960)

60Gy 75Gy

<2% 12%

Mazeron et al.,

>65Gy: 15-25%

<65Gy: 5-10%

P. Georg et al.,

IJROBP 2011

0

0,2

0,4

0,6

0,8

1

0 20 40 60 80 100120140160180

D2cm3)