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8

Recommendation of EMBRACE II:

Simultaneously integrated lymph node boost (SIB)

Simultaneously integrated lymph node boost:

IMRT

Dose planning with two dose levels

Elective target

Pathological lymph node target

In case of very big nodes: to consider a replan

after 20-25Gy

Recommended lymph node dose

in EMBRACE II

Total 60Gy EQD2

45Gy/25fx to elective CTV

55Gy/25fx (within pelvis: 3-4Gy BT)

57.5Gy/25fx (outside pelvis: 0Gy BT)

45Gy

55Gy