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Interpretation of RetroEMBRACE results

(IGABT compared to large population based cohorts using 2D BT)

Pelvic failure

(crude)

Concomitant

chemo

IB

IIB

IIIB

retroEMBRACE

(n=731)

77%

4%

11%

25%

Perez 1998

0%

12%

21%

41%

Barillot 1997

0%

13%

24%

49%

Improvement

Δ8-9% Δ10-13% Δ16-24%

Overall

Survival

Radio-chemo

retroEMBRACE

Consecutive

3D/4D IGABT

UK Survey

Vale 2010

2D BT

US SEER

2000-2009

2D BT

US NCDBA

2004-2011

2D BT

No of pts

394

471

3246

2571

5y OS

Improvement

67%

Reference

55%

Δ12%

55%

Δ12%

54%

Δ13%

13%

23%

Δ10

%

total