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Background / Introduction
Risk of nodal spread
Depth of invasion
Risk of Pelvic N+
< 3 mm
< 1%
3-5 mm
1 – 8 %
6 – 10 mm
15 %
11 – 15 mm
22 %
LVSI
Risk of Pelvic N+
Absent
8%
Present
25%
Inoue et al. Cancer 1984
Delgado G, et al. (GOG study). Gynecol Oncol 1989
Coia L, et al. Cancer 1990
Leibel & Philips Textbook
Surgical series
Risk of nodal disease related to stage, invasion depth and LVSI