Sub-study on nodal recurrence within
EMBRACE
(work in progress)
•
1077 patients, all stages cervix cancer, M0
•
Overall node control 93 % (at 2 years)
–
12 % recurrences in N1 patients
–
5 % in N0
•
At time of diagnosis majority of pathologic
nodes in the pelvis
•
At time of first relapse majority at upper field
border/PAO
,
Inside the field = problem with dose and detection
Outside and marginal = geographical miss
Nomden et al
Percentage of patients with pathologic
lymph nodes at time of diagnosis (left) and
the percentage of patients with nodal failure
(right) per nodal region
Patterns of regional recurrence after RT