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GTV for nodal RT boost

Imaging:

indirect proof (morphological & functional characteristics)

Consider nodal involvement if

1. Nodes are PET positive

Also PET negative nodes can contain metastases!

Small ones if cell load low

Big ones if large necrotic center

2. Nodes > 10 mm short axis diameter on CT or MRI

Can be reactive!

3. Nodes between 5 and 10 mm on MRI if

PET positive

Irregular shape

Lost nodal architecture

Inhomogeneous appearance (“necrotic center”)

Irregular border