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Locoregional Recurrence

RT

no RT

Logrank

N

192

196

F

104

107

P =0.48

RT

no RT

At risk:

192

196

146

134

112

105

31

26

RT

no RT

0

25

50

75

100

years

0

5

10

15

Cumulative percentage

Treatment arm

Failure free survival - HIR

RT

no RT

Logrank

N

192

196

F

12

39

P <.001

RT

no RT

At risk:

192

196

147

136

113

106

31

27

RT

no RT

0

20

30

years

0

5

10

15

Treatment arm

Locoregional relapse - HIR

Failure Free Survival

Creutzberg et al, ASTRO 2009, IJROBP 2011

75% vaginal

recurrences

PORTEC-1: 15-year outcomes for HIR patients