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Largest retrospective

analysis suggest benefit of

chemotherapy

Hasegawa K. Int J Gynecol Cancer 2014; Viswanathan Gynecol Onc 2011; Randall JCO 2006; Hogberg EJC 2010; De Boer ASCO 2017

Serous and clear cell

Subgroups in randomized trials, no clear benefit:

GOG-122

NSGO-EORTC/Iliade

PORTEC-3