702-703 / 1726
Molecular analysis PORTEC-1 and 2 cohort (N=834)
1 .0
ility o f
e n c e
p 5 3
M S I
P O L E
N SM P
P -
v a lu e < 0 .0 01
1 .0
ility o f
e n c e
p 5 3
M S I
P O L E
N SM P
P -
v a lu e < 0 .0 01
p 5 3
M S I
N SM P
P -
v a lu e < 0 .0 01
The 4 TCGA subgroups by surrogate markers
Locoregional recurrence
0
5
1 0
0 .0
0 .5
1 .0
T im e ( y e a rs )
p 5 3
M S I
L E
N SM P
P -
v a lu e < 0 .0 01
0
5
1 0
0 .0
0 .5
1 .0
T im e ( y e a rs )
C um u la tiv e p ro b a b ility o f
d is ta n t re c u rre n c e
p 5 3
M S I
P O L E
N SM P
P -
v a lu e < 0 .0 01
0
5
1 0
0 .0
0 .5
1 .0
T im e ( y e a rs )
O ve ra ll S u rv iva l
P -
v a lu e < 0 .0 01
Distant metastasis
Overall survival