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Chemistry and Properties of Aloin:
•
Yellow‐brown colored
latex constituent.
•
It is used as a stimulant‐
laxative before 2002.
•
Treating constipation by
inducing bowel
movements.
•
Found under the rind of
the aloe leaf and in
between it and the gel.
Regulations
•
Approved in the US in 1975 as an OTC drug to treat
chronic constipation, aloe latex is no longer approved for
such US use as of May 9, 2002
•
US FDA National Toxicology Program conducted toxicity
study on unpurified (high‐aloin) dry leaf juice
•
European Council Directive 88/388/EEC of 22 June 1988
ll
t 0 1 /k l i
f d/b
fl
i
a ows up o . mg g a o n as oo everage avor ng
•
Topical use in cosmetics up to 50 ppm of aloin is allowed
(CIR 2007)