626 / 815
3DCRT
vs.
IMRT
•
Retrospective study: MD Anderson
1996-2006
N= 496 NSCLC pts
CT/3DCRT: 318 pts, Fup mean Time: 2.1 y
4DCT/IMRT: 91 pts, Fup mean time: 1.3 y
Median dose of 63 Gy.
HR OS > 1 in favour of 4DCT/IMRT (trend for LRC
and DM)
Significantly lower toxicity with IMRT/4DCT
V20 was significantly higher in the 3DCRT group and
was a significant factor in determining toxicity.
Freedom from DM was nearly identical in both groups.