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Radical Conventional Radiotherapy

RTOG 73-01: 60 Gy> 50 Gy > 40 GY

o 1-year OS: same 40%

o 2 & 3-y OS: 20% vs 15% vs 10% (LC benefit)

Present Standard: > 60 Gy/ 30 fr, over 6 weeks

Local control: 16-60 %

[Arigada, 1992; Perez, 1982]

Radical Surgery : local control rate 80-95%