OMB Meeting Book (March 2, 2017)

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Department of Pharmacology, Robert Wood Johnson Medical School-UMDNJ, Piscataway, New
Jersey, USA
 Performed research in drug discovery and development of anti-AIDS and anti-cancer; Contributed
in drug design and structural optimization, drug synthesis and characterization, purification and
preformulation
 Conducted analytical and bioanalytical method development and validation of drug substance
 Performed separation, elucidation and identification of active pharmaceutical ingredient using
HPLC, LC-MS/MS, MALDI-TOF MS and NMR
 Conducted pharmaceutical analysis of biological samples to evaluate the pharmacokinetics and
elucidate the metabolite of organic drug compounds
 Conducted pegylation of active pharmaceutical ingredient to increase bioavailability and optimize
pharmacokinetics
 Performed design and optimization of drug structure to increase inhibition efficacy to fight AIDS
 Performed preparative separation to obtain the most active species against AIDS using semi-prep
and prep HPLC
Mar. 2005 - July 2007 Collaboration scientist
Novaflux Biosciences Inc., Princeton, New Jersey, USA
 Developed microbicides from homopolymer and copolymer of guanides and their derivatives
(PBGs) to prevent HIV-AIDS transmission
 Performed preformulation of topical microbicides as the fusion inhibitor of HIV type-1 virus
 Investigated the feasible applications of PBGs on other infectious diseases
 Conducted the characterization and identification of active pharmaceutical ingredient and drug
substance by NMR, HPLC, LC-MS/MS and MALDI-TOF MS
Sep.1999 - Dec. 2004 Research and Teaching Assistant
Department of Chemistry and Biochemistry, Auburn University, Auburn, AL
 Conducted qualitative and quantitative analytical method development and validation with HPLC,
HPAEC, IEC, LC-MS, GC-IR, GC-MS, ESI-MS and MALDI-TOF MS
 Developed electroactive polymers and completed characterization of their chemical and physical
properties by various techniques
 Performed isolation and identification of biological samples including proteins, peptides and
saccharides
 Developed a group of gas sensors with high selectivity and sensitivity for volatile organic
compounds (VOCs)
 Discovered the polymerization and redox switching mechanism using electrochemistry combined
with Electrochemical Quartz Crystal Microgravity
 Instructed Instrumental Analysis Lab, Chemical Analysis Lab and General Chemistry Lab;
Supervised and trained graduate and undergraduate students
July 1993 - Aug. 1999 Process Engineer
SINOPEC  Shanghai Engineering Company Limited (SSEC), Shanghai, P.R.China
 Conducted process evaluation and improvement, transferred manufacturing process from R&D to
operations
 Developed and designed process flow, plant layout, equipment and piping system
 Committed ANSI, API, cGMP and FDA requirement for chemical and pharmaceutical industries
 Conducted and evaluated on-site installation, troubleshooting, validation, start-up and commission
run test
 China Petrolum & Chemical Corporation
 Former Shanghai Pharmaceutical Industry Design Institute (SPIDI)
OMB Meeting Book 36
March 2, 2017