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Step 4: Defining MRI based (adaptive)

Volumes and Doses

ICRU 38 Revision Report committee

(1999-2016)

Gyn GEC ESTRO Working group/network

(2001-….)

ABS Recommendations

: (2005-2014)

Concept of Volume and Dose specification

volumetric GTV, (adaptive) CTV, OARs

residual GTV, CTV

HR

and CTV

IR

, D

90

, D

100

fixed absolute volumes for OAR, D

2cm3

, D

0.1cm3

Biological modelling: equi-effective dose (EQD2)

assessing different doses per fraction/dose rates

for GTV

res

, CTV

HR

, CTV

IR

, OAR

GYN GEC ESTRO recommendations I (Haie-Meder t al.) - contouring

GYN GEC ESTRO recommendations II (Pötter et al.) - dose vol. parameters

GYN GEC ESTRO recommendatio s III Hellebust et al.) - reconstruction

GYN GEC ESTRO recommendations IV (Dimopoulos et al.) - imaging

ABS recommendations n GYN ge eral (Viswanathan and Th madsen,

ABS Cervical Cancer Recommendations Committee) - general

ABS recommendations on GYN HDR (Viswanathan et al.)

ABS recommendations on GYN PDR (Lee et al.)