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State of art of radiation therapy in Esophageal Cancer
Preoperative
Chemoradiation
Planned Esophagectomy
• Walsh et al – 1996 (Trimodality)
SVV Benefit
• CROSS - 2015 (Trimodality)
SVV Benefit
• POET - 2009 (Trimodality)
NO SVV Benefit
• Urba et al – 2001 (Trimodality)
NO SVV Benefit
• Burmeister et al – 2005 (Trimodality)
NO SVV Benefit
• Tepper et al – 2008 (Trimodality)
SVV Benefit
• FFCD 9901 - 2014 (Trimodality)
NO SVV Benefit
Chemoradiation
or
Selective Esophagectomy
• FFCD 9102 - 2015
NO SVV Benefit
• ESSEN Trial - 2005
NO SVV Benefit
Definitive
Chemoradiation
Salvage Esophagectomy
• RTOG 85-01 - 1999
SVV Benefit
• INT 0123 - 2002
NO SVV Benefit