• CROSS - 2015 (Trimodality)
T1N1+T2-3N0-1M0
Junction= 24%
366 pts
Adeno 75%
Preoperative
Chemoradiation
Planned Esophagectomy
Treatemet related mortality
chemoradiotherapy + surgery:
4%
Van Hagen
et al
; N Engl J Med 2012
Oppedijk
et al;
JCO 2014
Shapiro
et al
; Lancet Oncol 2015
The Netherlands
surgery alone:
4%
p=ns