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Neoscope Study – Trial Design
RT
Cape
Cape Cape
Cape
Cape
Cape
OxCapRT Arm
:
Oxaliplatin 130mg/m
2
Day1 + Capecitabine 625mg/m
2
bd Day 1- 21 (2 cycles)
CRT:
Oxal 85mg/m
2
Days 1, 15, 29 + Cape 625mg/m
2
bd Mon-Fri
45 Gy in 25 fractions
Restaging CT/PET-CT
Surgery (6-8 weeks post CRT)
© Universitätsmedizin Leipzig: University Cancer Center Leipzig (UCCL), Prof. Dr. F. Lordick
Mukherjee S et al.
ASCO-GI
2016
R
Cape
RT
Oxaliplatin
Carboplatin/Paclitaxel
Follow up: 6 weeks, 6 & 12 months
45 Gy in 25 fractions
CarPacRT Arm
:
Oxaliplatin 130mg/m
2
Day 1 + Capecitabine 625mg/m
2
bd Day 1- 21 (2 cycles)
CRT:
Paclitaxel 50mg/m
2
& Carboplatin AUC 2 Days 1,8,15,22,29;